Ticker brief

ALNY ALNYLAM PHARMACEUTICALS INC

Consumer, Non-cyclical · Biotechnology

last close
$237.10
1 day
+0.2%
14 days
+3.7%
mkt cap
$41.8B
signals 14d
23
authors 14d
11
crowd 14d
-0.7σ
Options inteloptions-surface reads · latest available day per source
metricreadingcontext
IV — ATM 30d44% mid · 51 pctile own 1yIV/HV 0.52×
Skew — 25Δ RR 30d-0.016 80 pctile own 1ybalanced vs own range
Net dealer OI (NDOI)+0.43 elevated5-session Δ +0.16 (as of 2026-07-06)
OI alarmquietlast alarm 2025-10-10 (z=3.7)
Sentiment — last 14 days
daily mean sentiment, 2026-08-15 → 2026-08-28 · now -0.21 (−1 bearish … +1 bullish)
Who spoke11
authorgradetrader scoresignalsmean sent
@harry03994688A-0.798+0.59
@adamfeuersteinA+1.414-0.45
@semodoughC-3.012-0.12
@Markadiusz45C+1.182+0.20
@AktienTrader1C-0.141+0.35
@BullTheoryioC-1.571-0.43
@bioinvestor24A-0.451-0.15
@SpartanTradingC-1.461+0.00
@PersimmonTIA-0.571-0.75
@newsinvestingC·1+0.30
@fwpharmaB+0.981-0.15
Recent signals23of 23 in 14d — receipts included
date (PT)authorsentwhat they saidsince thenreceipt
2026-08-28@fwpharma-0.15Reports an AstraZeneca ATTR-CM study miss that raises questions for competing therapies.
2026-08-28@newsinvesting+0.30Reports ALNY falling on a rival trial while analysts view its core business as protected.
2026-08-28@harry03994688+0.50ESC 2026 heart-failure guidelines reportedly add Alnylam's vutrisiran as a class-I recommendation.
2026-08-28@adamfeuerstein-0.65Reports adverse CARDIO-TTRansform combination-arm data and negative interpretations from three sell-side analysts.
2026-08-28@PersimmonTI-0.75Argues stabilizer differences make ALNY's AMVUTTRA and next-generation silencer outlook worse.
2026-08-28@semodough-0.25Cites Wells Fargo's view that CARDIO-TTRansform data may require modification of ALNY's TRITON trial.
2026-08-28@adamfeuerstein-0.35Provides subgroup cardiovascular event-rate ratios from a study relevant to four amyloidosis drug companies.
2026-08-28@adamfeuerstein-0.35Reports a failed AstraZeneca heart-disease study and broader concerns for silencer drugs.
2026-08-27@harry03994688+0.50Advocates rotating from priced-in hardware toward software and AI-enabled biotechnology.+0.2%
2026-08-27@adamfeuerstein-0.45Highlights adverse read-through for Alnylam from a failed heart-drug study.+0.2%
2026-08-27@harry03994688+0.75Author says ALNY's technology leads competitors by roughly 10x and appears substantially undervalued.+0.2%
2026-08-26@harry03994688+0.75Calls ALNY the top mid-cap biotech with strong expansion and clinical success potential.-0.8%
2026-08-26@harry03994688+0.60Author compares biotech platforms and argues ABCL could join REGN and ALNY above a 50% approval-success potential.-0.8%
2026-08-25@harry03994688+0.35Author expresses enthusiasm for digital biology and directs readers to research ABCL and ALNY.-1.2%
2026-08-25@harry03994688+0.75Author is explicitly bullish only on ALNY due to claimed clinical-test improvements.-1.2%
2026-08-25@harry03994688+0.50The author contrasts RNA-silencing and mRNA platforms and outlines their distinct long-term therapeutic markets.-1.2%
2026-08-24@SpartanTrading+0.00Lists four chart ideas on watch for tomorrow without entry intent.+0.5%
2026-08-19@Markadiusz45+0.15Lists neglected RNA-related charts generated by ChatGPT.-2.3%
2026-08-19@Markadiusz45+0.25Suggests an emerging RNA-stock season and supplies a multi-name thematic basket.-2.3%
2026-08-16@bioinvestor24-0.15Questions KYMR's valuation, differentiation and development timeline while comparing peers and FOMO.+3.7%
2026-08-16@semodough+0.00Reports a KOL's TTR-CM patient mix, prevalence, diagnostic trends and 20% annual practice growth.+3.7%
2026-08-16@BullTheoryio-0.43Ranks the six worst Nasdaq 100 returns in 2026, each with losses.+3.7%
2026-08-15@AktienTrader1+0.35Suggests ALNY may have bottomed and notes profitability despite a 39 P/E.+3.7%

“Since then” = price move from the close on the signal's date (PT) to the latest close — what happened after they said it, not a backtest. A — means no trading session has closed since the signal yet. Sentiment is our extracted per-tweet score, −1…+1.