Ticker brief

ALNY ALNYLAM PHARMACEUTICALS INC

Consumer, Non-cyclical · Biotechnology

last close
$224.03
1 day
-1.4%
14 days
-3.7%
mkt cap
$41.8B
signals 14d
37
authors 14d
5
crowd 14d
+0.9σ
Options inteloptions-surface reads · latest available day per source
metricreadingcontext
IV — ATM 30d66% rich · 100 pctile own 1yIV/HV 1.75×
Skew — 25Δ RR 30d-0.004 91 pctile own 1ycalls bid vs puts (call skew rich)
Net dealer OI (NDOI)+0.43 elevated5-session Δ +0.16 (as of 2026-07-06)
OI alarmquietlast alarm 2025-10-10 (z=3.7)
CSP screenrank #5 · $207.5 strike · 1.06% premon the CSP screen (2026-10-23)
Sentiment — last 14 days
daily mean sentiment, 2026-10-02 → 2026-10-16 · now +0.53 (−1 bearish … +1 bullish)
Who spoke5
authorgradetrader scoresignalsmean sent
@harry03994688A-0.1632+0.60
@bioinvestor24A-0.872-0.23
@TickeronC+1.531-0.50
@DanielMuvdiYTB-2.111-0.35
@semodoughC-1.061+0.40
Recent signals30of 37 in 14d — receipts included
date (PT)authorsentwhat they saidsince thenreceipt
2026-10-16@harry03994688+0.45Expresses approval of Alnylam's culture and its continuity under the 2030 plan.-3.4%
2026-10-16@harry03994688+0.60Uses two large RNAi IPO financings and expanding indications to argue positively for Alnylam.-3.4%
2026-10-15@harry03994688+0.80Expresses high conviction in Alnylam's ongoing 2030 strategic plan and cultural continuity.-4.3%
2026-10-15@harry03994688+0.75Forecasts a long biotech bull market based on positioning, payer resilience, AI and a new FDA framework.-4.3%
2026-10-15@harry03994688+0.55Presents a bullish biotech basket thesis based on payer insulation, AI and improving clinical margins.-4.3%
2026-10-14@harry03994688+0.50Says a new rare-disease framework is favorable for ALNY and NTLA.-0.2%
2026-10-14@harry03994688+0.50Favors ALNY's focus on unmet, less-contested indications while noting ARWR's first drug overlaps Ionis.-0.2%
2026-10-14@harry03994688+0.40Says cash-rich, staple and healthcare companies benefit from high rates.-0.2%
2026-10-14@harry03994688+0.65After comparing Alzheimer's programs, explicitly says they are more bullish on ALNY.-0.2%
2026-10-14@harry03994688+0.50Calls siRNA a large market and praises Arrowhead's technology-0.2%
2026-10-13@harry03994688+0.10Mentions Alnylam's ALN-2232 program without a developed stance+0.1%
2026-10-13@harry03994688+0.70Presents mRNA and siRNA as transformative biotechnology platforms+0.1%
2026-10-13@harry03994688+0.80Expects Alnylam to lead ALK7 while viewing obesity as large enough for both firms+0.1%
2026-10-13@harry03994688+0.45Believes Alnylam can commercialize ALN-2232 itself, while noting uncertainty+0.1%
2026-10-13@harry03994688+1.00Extensive ALK7 obesity thesis concludes ALNY reaching a $1T valuation is unavoidable+0.1%
2026-10-13@harry03994688+0.35Expects Alnylam to commercialize ALN-2232 independently+0.1%
2026-10-13@harry03994688+0.50Views obesity as a lucrative market supporting self-commercialization by both firms+0.1%
2026-10-13@harry03994688+0.30Discloses holdings in RKLB, NTLA, and ALNY while noting extreme small-cap short positioning.+0.1%
2026-10-12@bioinvestor24-0.25Discloses no MRNA position and says it is fully valued while comparing past biotech valuations.-1.3%
2026-10-12@semodough+0.40Truist reiterates Buy with a $315 target and expects an in-line quarter and unchanged FY26 guidance.-1.3%
2026-10-12@harry03994688+0.70Long-form thesis says AI pressures conventional software and some biotech while favoring RNA/DNA drug companies.-1.3%
2026-10-11@harry03994688+0.15Explains that ALNY developed Leqvio and NVS commercializes it.-3.7%
2026-10-10@harry03994688+0.65Presents AMD, Rocket Lab, and Alnylam as long-duration growth opportunities created by temporary product setbacks.-3.7%
2026-10-09@harry03994688+0.30Connects RNA-Puzzles expertise at Inceptive AI with its collaboration to optimize Alnylam RNAi drugs.-3.7%
2026-10-09@harry03994688+0.60Presents AI-enabled biotech as a structural turnaround and highlights high-short-interest names benefiting from squeezes.-3.7%
2026-10-09@harry03994688+0.85Buy ALNY heavily after its 50% correction as its R&D breadth expands. — Calls the ALNY-Inceptive collaboration and pipeline expansion a strong buying moment.-3.7%
2026-10-09@bioinvestor24-0.20Mocks VKTX bear cases and predicts it will surpass INSM revenue before 2030 despite waiting for next year.-3.7%
2026-10-09@harry03994688+0.65Bullish long-term ALNY framework based on delivery, indications, manufacturing and AI R&D.-3.7%
2026-10-06@harry03994688+0.50Forecasts a biotech short squeeze driven by AI, improving success rates and falling long-term yields.+0.0%
2026-10-05@DanielMuvdiYT-0.35Despite prior gains in named stocks, warns that the market is very close to a violent decline.+1.9%

“Since then” = price move from the close on the signal's date (PT) to the latest close — what happened after they said it, not a backtest. A — means no trading session has closed since the signal yet. Sentiment is our extracted per-tweet score, −1…+1.